Przeciwciała przeciwko dekarboksylazie glutaminianowej w surowicy a zaburzenia neurologiczne: kiedy podejrzewać ich związek?
Goals: To discover completely different neurological manifestations with suspicion of being related to serum glutamate decarboxylase antibodies (GAD-Abs) in order to raised characterize anti-GAD neurological syndromes.
Strategies: Observational retrospective research together with all sufferers for whom GAD65-Abs titers in serum had been requested by the Neurology Division at La Paz College Hospital between 2015 and 2019. GAD-Abs had been measured by ELISA. Demographic knowledge, neurological signs, comorbidity with diabetes mellitus (DM) or with one other autoimmune illness, and GAD-Abs titers had been studied. Stiff-person syndrome, ataxia, encephalitis, and epilepsy had been thought-about typical anti-GAD neurological syndromes and had been in comparison with different atypical manifestations.
Outcomes: A complete of 173 sufferers (51.7% males, imply age 51.62) had been included. A progressive improve in requests of serum GAD-Abs has occurred over the past 5 years, particularly in sufferers with atypical neurological manifestations. GAD-Abs had been discovered within the serum of 22 sufferers (12.7%); of these, 15 (68.18%) suffered a typical anti-GAD syndrome. Presence of DM or one other organ-specific autoimmune illness was predictive of GAD-AB seropositivity (p < 0.001). 6.6% of requested sufferers with an atypical syndrome had GAD-Abs, however serum ranges had been considerably decrease than these present in sufferers with a typical syndrome (706.67 vs 1430.23 UI/mL; Mann-Whitney U, p = 0.034), and had been lastly recognized with one other neurological illness.
Conclusion: Serum GAD-Abs had been occasionally present in sufferers with medical phenotypes apart from these classically described as anti-GAD problems, and with very low titers. In typical anti-GAD syndromes, there’s a excessive comorbidity with DM and with different autoimmune illnesses, and excessive serum GAD-Abs ranges are often current.
Description: SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein).
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A (SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A(SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B (SEMA3B) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B(SEMA3B) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D (SEMA3D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D(SEMA3D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E (SEMA3E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E(SEMA3E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3F (SEMA3F) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3F(SEMA3F) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3G (SEMA3G) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3G(SEMA3G) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-4D (SEMA4D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-4D(SEMA4D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-7A (SEMA7A) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-7A(SEMA7A) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Semaphorin-3A in samples from serum, plasma, tissue homogenates and other biological fluids.
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Semaphorin-3F in samples from serum, plasma, tissue homogenates and other biological fluids.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 3E (SEMA3E) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 3E (SEMA3E) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 7A (SEMA7A) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 7A (SEMA7A) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3C(SEMA3C) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3C(SEMA3C) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3C(SEMA3C) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3D(SEMA3D) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3D(SEMA3D) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3D(SEMA3D) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
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Podwójne dodatnie wyniki przeciwciał przeciwko β 2 -glikoproteinie I domenie I i przeciw fosfatydyloserynie / protrombinie wzmacniają zarówno zakrzepicę, jak i dodatni wynik przeciwciał anty-ADAMTS13
Though just a few antiphospholipid syndrome (APS) happens with acquired thrombotic thrombocytopenic purpura (TTP), the connection between antiphospholipid antibodies (aPL) and anti-ADAMTS13 (anti-a disintegrin and metalloprotease with thrombospondin sort 1 motif, member 13) antibody stays unsure. We investigated the connection between high-risk thrombotic aPL and anti-ADAMTS13 antibody. 2 hundred and thirty-seven sufferers with optimistic lupus anticoagulant and/or anticardiolipin antibody had been included. Anti-β2GPI (anti-β2-glycoprotein I), anti-β2GPIdI (anti-β2-glycoprotein I area I), anti-PS/PT (anti-phosphatidylserine and prothrombin), ADAMTS13 exercise, and anti-ADAMTS13 antibody had been measured. Double positivity of anti-β2GPI and anti-PS/PT elevated thrombotic danger greater than three-fold and confirmed elevated positivity of anti-ADAMTS13 antibody compared with the double damaging group.
Double positivity of anti-β2GPIdI and anti-PS/PT offered each results much more. Within the linear regression evaluation, double positivity of anti-β2GPI and anti-PS/PT independently affected the anti-ADAMTS13 antibody stage (β = 1.982, P = 0.042). Our outcomes revealed that double positivity of anti-β2GPI or anti-β2GPIdI and anti-PS/PT elevated not solely thrombotic danger but in addition the positivity of anti-ADAMTS13 antibody, particularly indicating anti-β2GPIdI confirmed the next synergistic impact with anti-PS/PT. We propose a doable affiliation of anti-ADAMTS13 antibody with a excessive thrombotic danger of APS.
Double positivity of anti-β2GPI (anti-β2-glycoprotein I) and anti-PS/PT (anti-phosphatidylserine and prothrombin) antibodies enhanced not solely thrombotic danger but in addition positivity of anti-ADAMTS13 (anti-a disintegrin and metalloprotease with thrombospondin sort 1 motif, member 13) antibody. Moreover, double positivity of anti-β2GPIdI (anti-β2-glycoprotein I area I) mixed with anti-PS/PT much more elevated each thrombosis and positivity of anti-ADAMTS13 antibody. Double positivity of β2GPI and anti-PS/PT was discovered as an independently vital contributing issue to anti-ADAMTS13 antibody stage. We propose the affiliation between anti-ADAMTS13 antibody and the pathophysiology of antiphospholipid syndrome, which ought to be additional evaluated.
Strukturalny wpływ glikodendrymerów rekrutujących przeciwciała (ARG) na cytotoksyczność przeciwnowotworową
The recruitment of endogenous antibodies in opposition to most cancers cells has turn into a dependable antitumoral immunotherapeutic various over the past decade. The covalent attachment of antibody and tumor binding modules (ABM and TBM) inside a single, well-defined artificial molecule was certainly demonstrated to advertise the formation of an interacting ternary complicated between each the antibodies and the focused cell, which often leads to the simultaneous immune-mediated mobile destruction. In a preliminary research, we’ve got described the first Antibody Recruiting Glycodendrimers (ARGs), combining cRGD as ligands for the αVβ3-expressing melanoma cell line M21 and Rha as ligand for pure IgM, and demonstrated that multivalency is an important requirement to type this complicated.
Within the current research, we synthesized a brand new collection of ARGs composed of ABMs, i.e. self-condensed rhamnosylated cyclopeptide and polylysine dendrimer, which have been conjugated to the TBM with or with out spacer. Circulation cytometry and confocal microscopy experiments with human serum and completely different cell traces revealed that the ABM geometry considerably influences the ternary complicated formation in M21, whereas no vital binding happens in BT 549 having low integrin expression.
As well as, we exhibit with a mobile viability assay that ARGs induce excessive stage of cytotoxicity in opposition to M21 which can be in shut correlation with the ABM construction. Particularly, we’ve got proven that ARG combining cyclopeptide core and branches, with or with out spacer, induce 40-57% of selective cytotoxicity in opposition to M21 cells within the presence of human serum because the distinctive supply of immunity effectors. Lastly, we additionally spotlight that the spacer between ABM and TBM allows a rise of the immune-mediate cytotoxicity even with ABM of decrease valency.
ICELISA na bazie przeciwciał monoklonalnych do badania przesiewowego diazynonu w próbkach warzyw
Diazinon (DAZ) is an organophosphorus pesticide (OP), which is usually used to stop and management dangerous pests that endanger agricultural merchandise. On this research, we developed a novel heterology coating technique for the immunoassay of DAZ. The DAZ coating hapten may be instantly conjugated to the provider protein with out requiring a spacer arm. This proposed hapten coating technique is time-saving and considerably improves the sensitivity of the immunoassay as a result of lack of a spacer arm. The as-synthesized coating antigen was used to display screen the monoclonal antibody (mAb).
Lastly, the developed oblique aggressive enzyme-linked immunoassay (icELISA) confirmed IC50 and restrict of detection (LOD) values of 0.58 ng mL-1 and eight pg mL-1, respectively. This technique exhibited negligible cross-reactivity in direction of different analogues, and the recoveries of samples (cucumber, cabbage, and lettuce) ranged from 92.6% to 125.4%, with coefficients of variance (CV) under 12%. Good correlation between icELISA and high-performance liquid chromatography mass spectrometry (HPLC-MS/MS) was obtained. The proposed icELISA was an excellent software for monitoring DAZ residues in meals samples.
Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical.
Description: Quantitativesandwich ELISA kit for measuring Human Neurotrophin-3, NT-3 in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human Neurotrophin-3, NT-3 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Human 3-nitrotyrosine (3-NT) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human 3-nitrotyrosine (3-NT) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: The plasma concentrations of both the N-terminal fragment of Pro-B-type natriuretic peptide (NT-proBNP) and prohormone of brain natriuretic peptide (proBNP) are significantly increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
Description: The plasma concentrations of both the N-terminal fragment of Pro-B-type natriuretic peptide (NT-proBNP) and prohormone of brain natriuretic peptide (proBNP) are significantly increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
Description: Description of target: Neurotrophin-3 (NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system. NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3; also called TrkC), are expressed early and throughout embryogenesis. NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation. NT-3 may be one of the central nervous system-derived factors that mediate neural crest (NC) cell proliferation in vivo.4 NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 2 pg/mL
Description: Neurotrophin-3 Human Recombinant produced in E.Coli is a non-glycosylated and non-covalently linked homodimer, containing 2x119 amino acid chains, having a total Mw of 27.2 kDa.;The NT-3 is purified by proprietary chromatographic techniques.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is unconjugated.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is unconjugated.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to APC .
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Biotin.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to FITC.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to HRP.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to PerCP.
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to RPE .
Description: A polyclonal antibody for PUMA from Human | Rat | Rainbow Trout (Oncorhynchus mykiss). The antibody is produced in rabbit after immunization with Human N-terminal amino acids of human PUMA. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:500), IHC (1:100). This PUMA antibody is conjugated to Streptavidin.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is unconjugated.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is unconjugated.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to APC .
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Biotin.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to FITC.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to HRP.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to PerCP.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to RPE .
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is conjugated to Streptavidin.
Description: A polyclonal antibody for Calnexin from Human | Mouse | Rat | Bovine | Chicken | Dog | Guinea Pig (Cavia porcellus) | Hamster | Pig | Monkey | rabbit | Sheep | African clawed frog (Xenopus laevis) . The antibody is produced in rabbit after immunization with Human A 19 residue synthetic peptide based on dog calnexin and the peptide coupled to KLH. The Antibody is tested and validated for WB, IHC, ICC/IF, IP assays with the following recommended dilutions: WB (1:5000), IHC (1:100), ICC/IF (1:100), IP (1:100). This Calnexin antibody is unconjugated.
Description: Quantitative sandwich ELISA for measuring Human 3-nitrotyrosine (3-NT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Description: Quantitative sandwich ELISA for measuring Human 3-nitrotyrosine (3-NT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Description: Quantitative sandwich ELISA for measuring Human 3-nitrotyrosine (3-NT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NT-3 . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody for detection of NT-3 from Human, Mouse, Rat. This NT-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
Description: A polyclonal antibody for detection of NT-3 from Human, Mouse, Rat. This NT-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
Description: A polyclonal antibody for detection of NT-3 from Human, Mouse, Rat. This NT-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
